In this vivid and compelling novel, Tim Murphy follows a diverse set of characters whose fates intertwine in an iconic building in Manhattan's East Village, the Christodora. The Christodora is home to Milly and Jared, a privileged young couple with artistic ambitions. Their neighbor, Hector, a Puerto Rican gay man who was once a celebrated AIDS activist but is now a lonely addict, becomes connected to Milly's and Jared's lives in ways none of them can anticipate. Meanwhile, the couple's adopted son, Mateo, grows to appreciate the opportunities for both self-realization and oblivion that New York offers. As the junkies and protestors of the 1980s give way to the hipsters of the 2000s and they, in turn, to the wealthy residents of the crowded, glass-towered city of the 2020s, enormous changes rock the personal lives of Milly and Jared and the constellation of people around them.