This 64GB RAM is 100% compatible with Dell Precision 5820 Tower (Intel Xeon CPU W-21xx). Information on memory configurationThe following technical specifications should be observed in advance:RDIMM (Registered DIMM) or LRDIMM (Load Reduced DIMM) RAM memory can be installed in the device. LRDIMM memories are recommended if large memory capacities are to be achieved.RDIMM memory modules cannot be mixed with LRDIMM memories.If a memory expansion is to be carried out with the existing RAM memory, it must be checked which memory technology (RDIMM / LRDIMM) is available.A higher memory clock of the memory module automatically adapts to the memory clock specified by the system. This may be the case with larger capacities in particular.