Mafia III takes place in the open world of New Bordeaux, a reimagined version of the turbulent New Orleans of 1968, complete with era-inspired cars, fashion, and music. After years of fighting in Vietnam, Lincoln Clay has come to understand one thing: family is not about who you were born to – it’s about the people you would die for. Back in his hometown of New Bordeaux, Lincoln wants to leave his criminal past behind.

However, when his surrogate family, the Black mob, is betrayed and murdered by the Italian Mafia, Lincoln builds a new family from the ashes of his old world and embarks on a military-scale quest for revenge against those responsible. To survive in the streets of New Bordeaux, one must master wild shootouts, brutal fistfights, high-speed maneuvers, tough decisions, and street tricks. But with the right people, you can rise to the top of the city's underworld.