The speed will not differ, because the same disks with the same data transfer rate are always inside the external enclosures. The Ultra usually refers more to additional accessories, e.g. rescue software or similar.
A tip from me: the Seagate 5TB disks are cheaper, by the way, and there are always real SATA hard disks in the external enclosures from Seagate, which cannot be guaranteed with WD or other providers. Real SATA disks have the huge advantage that if the external enclosure motherboard in such an enclosure should ever be broken, then you can simply remove the Seagate disk from the external enclosure and read it out on a normal SATA interface.
Here, for example, is an example of a 5TB Seagate drive connected externally via USB 3.0. There is always a Seagate Barracuda 5TB hard drive inside (Seagate does not build hard drives with a direct USB connection):
Seagate Expansion Portable (5 TB)