Hello Snuppi

You can set up exclusion zones on all devices that use Imprint™ technology, i.e. Roomba i- and s-series.
On the Roomba 976 you can set up exclusion zones using the virtual walls:
iRobot Roomba Dual Mode
iRobot Roomba "Dual Mode" Twin Pack

Best regards
Your iRobot Team

No
It is only possible with the Virtual Wall.