The AsRock B550M Pro4 motherboard is compatible with 4th generation Ryzen 5 processors, which includes the Ryzen 5 5600, but it's crucial to make sure the BIOS version is up to date to properly support the processor. For gaming with a Ryzen 5 5600, this motherboard should be sufficient, but check RAM compatibility and make sure the BIOS is updated to avoid any problems.