That should work, since you can install 2x 140mm fans at the front. You would just have to check the dimensions of the case, your graphics card and the AIO so that they don't get in each other's way. With a 2-fan card, however, this should work easily.

Yes it works, but very badly. The hoses have almost no space and depending on the length there are also problems. I cannot recommend the housing for AIO.