According to the ASUS website, this memory (HX421C14FB2K2/16) is not compatible with the ASUS Z170 Pro Gaming. I refer to the lists that ASUS publishes on its website in the support section.
By the way, this memory (HX421C14FB2K2/16) is also not allowed for the ASUS Z170-Pro, the ASUS Z170-A, the ASUS Z170-E, the Z170-P, the ASUS Z170-K, ...
I then did not check the remaining 9 of the 15 variants of the ASUS Z170 series further, as the samples leave me little doubt that this memory (HX421C14FB2K2) should not be used with this series motherboard. In case of problems, the manufacturer can point out to the customer that unapproved memory is being used!

Hello proskilla

The RAM works with your mainboard ;)