This 4GB memory is 100% compatible with MSI Gaming Z97-G43.
Helping you choose the right memory:We offer the faster 1600MHz memory for your system.Due to the backwards compatibility of our memory to 1333MHz, you can also use them mixed with existing 1333MHz memory.Memory with ECC offers higher security through error detection and error correction. The ECC function is supported when ALL existing memories are equipped with ECC. You should use the UDIMM ECC memory if existing memory is equipped with ECC. The use of different ram sizes in the slots is possible.The Dual Channel Mode is also supported here by the Intel Flex Memory technology. With different RAM capacities, you must ensure that the memories in memory channel A are larger than the memories in memory channel B.