This 32GB RAM is 100% compatible with Dell PowerEdge R320. Information regarding memory configuration: The following technical specifications should be considered in advance: RDIMM (Registered DIMM) or LRDIMM (Load Reduced DIMM) RAM can be installed in the device. LRDIMM memory is recommended when large memory capacities are to be achieved. RDIMM memory modules cannot be mixed with LRDIMM memory. If a memory upgrade is to be made with the existing RAM, it must be checked which memory technology (RDIMM / LRDIMM) is present. Memory slots without a processor must not be populated. A higher memory clock speed of the memory module automatically adjusts to the memory clock speed set by the system. This can especially be the case with larger capacities.