Yes, you can connect the PlayStation 5 Slim Disk Edition and a PC to a monitor at the same time so that both run independently of each other. The prerequisite is that your monitor has multiple inputs, for example an HDMI connection for the PS5 and a DisplayPort connection for the PC. You can then change the input source on the monitor to switch between PS5 and PC. Both devices are connected independently, but you cannot see both image signals on the monitor at the same time, you have to switch the source.